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- 827830 description "The mix of academic institutions, research centres, and healthcare facilities in Ghent has nurtured a flourishing healthtech ecosystem." news.
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- 827830 url discover-synergy-between-biotech-medtech-and-digital-health-ghent-european-technology-capital news.
- 827830 dateModified "2024-10-25T13:15:48+00:00" news.
- 827830 datePublished "2024-10-25T13:15:48+00:00" news.
- 827830 headline "Discover the synergy between biotech, medtech and digital health in Ghent, a European technology capital" news.
- 827830 articleBody " <div class="paragraph paragraph--type--text paragraph--view-mode--full"> <p><span lang="EN-GB">When you think about Ghent, do you think about its historic city centre, with the Castle of the Counts and its intricate network of canals and waterways? Sure, but do you also think about how it’s poised to become the European Technology Capital?</span></p><p><span lang="EN-GB">Mixing excellent infrastructure, talented individuals working on the modern miracles of tomorrow and fostering regular collaboration between research organisations and business solutions, one can witness this city's captivating and vibrant energy. The proof of the pudding is in the eating, and that’s also true of Ghent’s vibrant healthtech cluster.</span></p><p><span lang="EN-GB">With seamless cooperation between life sciences, medtech, and digitech, it attracts investments and offers comprehensive support structures. In this article, we examine Ghent's captivating healthtech cluster to learn why it should also be on your radar.</span></p> </div> <div class="paragraph paragraph--type--image paragraph--view-mode--full"> <div class="image-gallery--wrapper single"> <div class="image-gallery js-lightbox"> <a href="https://stad.gent/sites/default/files/styles/gallery_full/public/media/images/Stad%20Gent%203.jpg?itok=7rBWhoJd" class="gallery-link" aria-describedby="image-gallery__open-gallery" > <figure> <picture> <source srcset="/sites/default/files/styles/wide_l/public/media/images/Stad%20Gent%203.jpg?itok=qZPal8Rg 1x, /sites/default/files/styles/wide_l_x2/public/media/images/Stad%20Gent%203.jpg?itok=CAqeujxb 2x" media="(min-width: 1680px)" type="image/jpeg" width="655" height="437"/> <source srcset="/sites/default/files/styles/wide_l/public/media/images/Stad%20Gent%203.jpg?itok=qZPal8Rg 1x, /sites/default/files/styles/wide_l_x2/public/media/images/Stad%20Gent%203.jpg?itok=CAqeujxb 2x" media="all and (min-width: 960px) and (max-width: 1679.9px)" type="image/jpeg" width="655" height="437"/> <source srcset="/sites/default/files/styles/wide_xxl/public/media/images/Stad%20Gent%203.jpg?itok=nwlc0Mpf 1x, /sites/default/files/styles/wide_xxl_x2/public/media/images/Stad%20Gent%203.jpg?itok=uuVWSKPZ 2x" media="all and (min-width: 768px) and (max-width: 959.9px)" type="image/jpeg" width="920" height="614"/> <source srcset="/sites/default/files/styles/wide_xl/public/media/images/Stad%20Gent%203.jpg?itok=tKoph7TU 1x, /sites/default/files/styles/wide_xl_x2/public/media/images/Stad%20Gent%203.jpg?itok=hNNybrak 2x" media="all and (min-width: 576px) and (max-width: 767.9px)" type="image/jpeg" width="727" height="485"/> <source srcset="/sites/default/files/styles/wide_m/public/media/images/Stad%20Gent%203.jpg?itok=ESFZVInv 1x, /sites/default/files/styles/wide_m_x2/public/media/images/Stad%20Gent%203.jpg?itok=r1AHaT1y 2x" media="all and (max-width: 575.9px)" type="image/jpeg" width="575" height="384"/> <img loading="lazy" src="/sites/default/files/styles/wide_xxl_x2/public/media/images/Stad%20Gent%203.jpg?itok=uuVWSKPZ" width="1840" height="1228" alt="Gravensteen" /> </picture> </figure> </a> </div> </div> </div> <div class="paragraph paragraph--type--text paragraph--view-mode--full"> <h2><span lang="EN-GB"><strong>A healthy ecosystem</strong></span></h2><p><span lang="EN-GB">The convergence of academic institutions, research centres, and healthcare facilities in Ghent has nurtured a flourishing ecosystem, with ground-breaking technologies and solutions.</span></p><p><span lang="EN-GB">One of the central actors is </span><a href="https://vib.be/en#/"><span lang="EN-GB">VIB</span></a><span lang="EN-GB">, the Flemish Institute for Biotechnology. Anchored at </span><a href="http://www.techlane.be/about/"><span lang="EN-GB">Tech Lane Ghent Science Park</span></a><span lang="EN-GB">, it is a facility where multidisciplinary life sciences research is conducted. Their dedicated team of researchers explores molecular mechanisms across various organisms, aiming for tangible societal impact through their technology transfer approach. One focus area is the use of llama antibodies, which have potential applications in cancer, inflammatory diseases, and viral infections. To enhance their research capacities, VIB and Ghent University have opened a new research building. Accommodating 200 researchers and a state-of-the-art BioSafety Level 3 facility offers a space for experimental research on airborne pathogens.</span></p><p><span lang="EN-GB">This brings us to another key contributor to this ecosystem: </span><a href="https://www.ugent.be/en"><span lang="EN-GB">Ghent University</span></a><span lang="EN-GB">, renowned for its focus on health and medical sciences. This educational powerhouse serves as a magnet for the world's most promising talents in medicine and related fields. Its diverse departments focus on addressing the challenges of diagnosing rare diseases, understanding mechanisms, and developing therapies. They also educate future researchers and professionals and are involved in advisory and decision boards, which help guide patient-centred research and education.</span></p><p><span lang="EN-GB">Situated in the southern region of Ghent, </span><a href="https://uzgent.be/"><span lang="EN-GB">UZ Ghent</span></a><span lang="EN-GB"> serves as the city’s university hospital and is a central component of the health ecosystem. With a strong track record, the hospital conducts over 1,900 clinical experiments and 900 clinical studies annually. UZ Ghent acknowledges the importance of translating research into practical applications. It is expanding its clinical GMP unit for cell and gene therapy with lentiviral vector production capabilities, enabling faster development of innovative treatments like CAR-T for cancer and infectious diseases.</span></p><p><span lang="EN-GB">Playing a pivotal role in the region, </span><a href="https://flanders.bio/en"><span lang="EN-GB">Flanders.bio</span></a><span lang="EN-GB"> serves as a vibrant life sciences cluster organisation, fostering collaboration and networking within the healthtech sector. Through diverse activities and initiatives, it aims to bolster the Flemish region's standing in biotechnology, pharmaceuticals, and healthcare. Flanders.bio facilitates internationalisation, provides essential services, and builds expertise, ultimately nurturing a robust health ecosystem in Ghent and beyond.</span></p><p><span lang="EN-GB">Another research institute Ghent couldn’t do without is </span><a href="https://www.imec-int.com/en"><span lang="EN-GB">imec</span></a><span lang="EN-GB">, which specialises in integrated circuits, sensors, smart health solutions, and life sciences. Its research focuses on improving healthcare delivery, diagnostic and treatment methods, and promoting individual empowerment in health management. Imec collaborates with organisations to develop and validate innovative personalised and preventive healthcare technologies. By merging life sciences with digital technology, imec also enables enhanced measurement precision and efficient handling, storage, and utilisation of large datasets. </span></p><p><span lang="EN-GB">And let’s not forget </span><a href="https://www.imecistart.com/en"><span lang="EN-GB">imec.istart</span></a><span lang="EN-GB">, imec’s business accelerator, the first investor and supporting partner to scale tech startups. Its program offers a broad range of services such as initial financial injection, personal coaching and mentoring, access to technology and working facilities, access to a vast (inter)national network of partners and investors and more. Since its launch in 2011, imec.istart has helped more than 290 tech startups in diverse fields to develop into sustainable ventures. Last May, the organisation was ranked the world's best university-linked Business Accelerator by UBI Global during the World Incubation Summit.</span></p> </div> <div class="paragraph paragraph--type--image paragraph--view-mode--full"> <div class="image-gallery--wrapper single"> <div class="image-gallery js-lightbox"> <a href="https://stad.gent/sites/default/files/styles/gallery_full/public/media/images/UZ%20Gent.jpg?itok=GnJiqSK0" class="gallery-link" aria-describedby="image-gallery__open-gallery" > <figure> <picture> <source srcset="/sites/default/files/styles/wide_l/public/media/images/UZ%20Gent.jpg?itok=xjd0XH2Z 1x, /sites/default/files/styles/wide_l_x2/public/media/images/UZ%20Gent.jpg?itok=SRq9HfJG 2x" media="(min-width: 1680px)" type="image/jpeg" width="655" height="313"/> <source srcset="/sites/default/files/styles/wide_l/public/media/images/UZ%20Gent.jpg?itok=xjd0XH2Z 1x, /sites/default/files/styles/wide_l_x2/public/media/images/UZ%20Gent.jpg?itok=SRq9HfJG 2x" media="all and (min-width: 960px) and (max-width: 1679.9px)" type="image/jpeg" width="655" height="313"/> <source srcset="/sites/default/files/styles/wide_xxl/public/media/images/UZ%20Gent.jpg?itok=fbTv0rXK 1x, /sites/default/files/styles/wide_xxl_x2/public/media/images/UZ%20Gent.jpg?itok=ACYrrjdu 2x" media="all and (min-width: 768px) and (max-width: 959.9px)" type="image/jpeg" width="920" height="439"/> <source srcset="/sites/default/files/styles/wide_xl/public/media/images/UZ%20Gent.jpg?itok=AQpjRcaG 1x, /sites/default/files/styles/wide_xl_x2/public/media/images/UZ%20Gent.jpg?itok=5neaxZU2 2x" media="all and (min-width: 576px) and (max-width: 767.9px)" type="image/jpeg" width="727" height="347"/> <source srcset="/sites/default/files/styles/wide_m/public/media/images/UZ%20Gent.jpg?itok=Amp3K06S 1x, /sites/default/files/styles/wide_m_x2/public/media/images/UZ%20Gent.jpg?itok=5JPPxcW0 2x" media="all and (max-width: 575.9px)" type="image/jpeg" width="575" height="275"/> <img loading="lazy" src="/sites/default/files/styles/wide_xxl_x2/public/media/images/UZ%20Gent.jpg?itok=ACYrrjdu" width="1840" height="879" alt="UZ Gent" /> </picture> </figure> </a> </div> </div> </div> <div class="paragraph paragraph--type--text paragraph--view-mode--full"> <p><span lang="EN-GB"><strong>Fostering startups</strong></span></p><p><span lang="EN-GB">Several local healthtech companies begin as spin-offs from these actors, while new collaborations also serve as a magnet for attracting additional companies.</span></p><p><span lang="EN-GB">For example, </span><a href="https://www.sanofi.com/en"><span lang="EN-GB">Ablynx</span></a><span lang="EN-GB"> has emerged as a frontrunner in human therapeutic innovation among the VIB-inspired spin-offs. The company has achieved success in developing caplacizumab, the world's first medication for acquired thrombotic thrombocytopenic purpura (aTTP), a rare blood clotting disorder, through the discovery and development of NANOBODY®-derived medicines, based on llama derived antibodies. Sanofi's recognition of Ablynx's achievements led to its acquisition for €3.9 billion in 2018. </span></p><p><a href="https://agomab.com/"><span lang="EN-GB">Agomab</span></a><span lang="EN-GB">, also inspired by VIB, leverages extensive expertise in growth factor biology to spearhead the development of ground-breaking treatments. The primary focus is tackling fibrosis, promoting tissue structure repair, and restoring organ function. </span></p><p><span lang="EN-GB">Another spin-off, </span><a href="https://www.confotherapeutics.com/"><span lang="EN-GB">Confo Therapeutics</span></a><span lang="EN-GB">, specialises in GPCRs, a type of membrane receptor widely targeted in drug discovery. With a unique discovery engine, Confo precisely targets desired GPCR conformations, unlocking significant potential for breakthrough medicines. </span></p><p><span lang="EN-GB">VIB is also closely collaborating with </span><a href="https://orionisbio.com/"><span lang="EN-GB">Orionis Biosciences</span></a><span lang="EN-GB">, an early-stage company propelling advancements in critical fields such as oncology and immunotherapies. Last year, this company captured the scientific community's attention with a $55 million financing round to support advancement into the clinic.</span></p><p><span lang="EN-GB">Ghent University also plays a pivotal role in fostering innovation. </span><a href="https://cespe.be/"><span lang="EN-GB">CESPE</span></a><span lang="EN-GB"> is one of its offspring, an accelerator focusing on the sustainable development, design, and optimisation of drug substance and product production platforms. This group has forged partnerships with local players such as </span><a href="https://rheavita.com/"><span lang="EN-GB">Rheavita</span></a><span lang="EN-GB"> and </span><a href="https://www.am-team.com/"><span lang="EN-GB">AM-Team</span></a><span lang="EN-GB"> and renowned multinationals such as </span><a href="https://www.janssen.com/belgium/"><span lang="EN-GB">Janssen</span></a><span lang="EN-GB">, </span><a href="https://www.takeda.com/en-be/"><span lang="EN-GB">Takeda</span></a><span lang="EN-GB">, </span><a href="http://www.pfizer.be"><span lang="EN-GB">Pfizer</span></a><span lang="EN-GB">, and </span><a href="https://www.cognizant.com/be/en"><span lang="EN-GB">Cognizant</span></a><span lang="EN-GB">. CESPE will relocate labs to state-of-the-art GMP-like facilities by the end of 2025, enabling pioneering research on pharmaceutical and biopharmaceutical compounds.</span></p><p><span lang="EN-GB">Where like-minded people come together, innovation thrives. Another platform is </span><a href="https://gatehealth.be/"><span lang="EN-GB">GATE</span></a><span lang="EN-GB">, which connects researchers, industry, and clinicians to harness emerging gene, cell, and tissue engineering technologies to revolutionise disease treatment, artificial organ development, and organ-on-chip technology. GATE's focus includes reconstructive surgery, cancer, neurological and cardiac syndromes, as well as eye and hearing issues. Moreover, these advancements have implications beyond healthcare, benefiting areas such as drug screening, medical devices, and cultured meat.</span></p><p><span lang="EN-GB">These platforms have brought forth notable companies like Ziphius and anacura. </span><a href="https://ziphius.org/"><span lang="EN-GB">Ziphius</span></a><span lang="EN-GB"> utilises its self-amplifying RNA platform to drive the development of vaccines for infectious diseases and gene supplementation therapies for rare genetic disorders. Meanwhile, </span><a href="https://www.anacura.com/en"><span lang="EN-GB">Anacura</span></a><span lang="EN-GB"> stands as an independent analytical centre of excellence in healthcare and drug development. The GMP unit for gene and cell therapy at Ghent University Hospital closely collaborates with local companies, producing the GMP batches of the Ziphius vaccines for phase 1 and 2 clinical trials. </span></p><p><span lang="EN-GB">CAR-T therapy, a widely-recognised form of cell therapy, shows immense promise in immunotherapy. This innovative treatment involves extracting, genetically modifying, and reintroducing the patient's own cells to enhance their ability to combat diseases like cancer. Harmless viral vectors act as vehicles to deliver genetic material during gene therapy or facilitate genetic modification in laboratory settings. These ground-breaking local advancements are partly why </span><a href="https://legendbiotech.com/"><span lang="EN-GB">Legend Biotech</span></a><span lang="EN-GB"> and </span><a href="https://www.janssen.com/belgium/discover-janssen"><span lang="EN-GB">Janssen</span></a><span lang="EN-GB"> chose Ghent to construct their joint, state-of-the-art facility located at Tech Lane Ghent Science Park. In 2025, they will put their cleanrooms to use and start offering life-changing CAR-T therapy. </span></p><p><span lang="EN-GB">Next to that, Ghent has also become known as a hub for expertise in the field of autoimmune diseases. </span><a href="https://www.argenx.com/"><span lang="EN-GB">Argenx</span></a><span lang="EN-GB">, for example, conducts advanced testing for various rare autoimmune diseases, including ITP (the destruction of blood platelets), pemphigus (a skin disease), and CIDP (the impairment of nerve pathways in the arms and legs). Recently, the company received FDA approval for the subcutaneous formulation of their first FcRn blocker for anti-acetylcholine receptor (AChR) antibody-positive generalised myasthenia gravis. </span></p> </div> <div class="paragraph paragraph--type--image paragraph--view-mode--full"> <div class="image-gallery--wrapper single"> <div class="image-gallery js-lightbox"> <a href="https://stad.gent/sites/default/files/styles/gallery_full/public/media/images/Stad%20Gent%201.jpg?itok=FfKBUSS3" class="gallery-link" aria-describedby="image-gallery__open-gallery" > <figure> <picture> <source srcset="/sites/default/files/styles/wide_l/public/media/images/Stad%20Gent%201.jpg?itok=9eB7ih4i 1x, /sites/default/files/styles/wide_l_x2/public/media/images/Stad%20Gent%201.jpg?itok=hfu2Nxqu 2x" media="(min-width: 1680px)" type="image/jpeg" width="655" height="437"/> <source srcset="/sites/default/files/styles/wide_l/public/media/images/Stad%20Gent%201.jpg?itok=9eB7ih4i 1x, /sites/default/files/styles/wide_l_x2/public/media/images/Stad%20Gent%201.jpg?itok=hfu2Nxqu 2x" media="all and (min-width: 960px) and (max-width: 1679.9px)" type="image/jpeg" width="655" height="437"/> <source srcset="/sites/default/files/styles/wide_xxl/public/media/images/Stad%20Gent%201.jpg?itok=cg2IiG3v 1x, /sites/default/files/styles/wide_xxl_x2/public/media/images/Stad%20Gent%201.jpg?itok=sI1yMkVR 2x" media="all and (min-width: 768px) and (max-width: 959.9px)" type="image/jpeg" width="920" height="614"/> <source srcset="/sites/default/files/styles/wide_xl/public/media/images/Stad%20Gent%201.jpg?itok=_F1VzQTo 1x, /sites/default/files/styles/wide_xl_x2/public/media/images/Stad%20Gent%201.jpg?itok=yxNdT79L 2x" media="all and (min-width: 576px) and (max-width: 767.9px)" type="image/jpeg" width="727" height="485"/> <source srcset="/sites/default/files/styles/wide_m/public/media/images/Stad%20Gent%201.jpg?itok=f4giRY_5 1x, /sites/default/files/styles/wide_m_x2/public/media/images/Stad%20Gent%201.jpg?itok=dVcOYGXN 2x" media="all and (max-width: 575.9px)" type="image/jpeg" width="575" height="384"/> <img loading="lazy" src="/sites/default/files/styles/wide_xxl_x2/public/media/images/Stad%20Gent%201.jpg?itok=sI1yMkVR" width="1840" height="1228" alt="Dokken" /> </picture> </figure> </a> </div> </div> </div> <div class="paragraph paragraph--type--text paragraph--view-mode--full"> <p><span lang="EN-GB"><strong>The new generation</strong></span></p><p><span lang="EN-GB">While these established players dominate the healthtech scene, imec.istart is experiencing a rise in a new breed of life science startups, nurturing the growth of companies like Ontoforce and IntelliProve.</span></p><p><a href="https://www.ontoforce.com/"><span lang="EN-GB">Ontoforce</span></a><span lang="EN-GB"> has been at the forefront for over a decade now, working on integrating data to unlock transformative insights, accelerate drug discovery, streamline clinical trial research, and establish a faster time-to-market. And </span><a href="https://www.intelliprove.com/"><span lang="EN-GB">IntelliProve</span></a><span lang="EN-GB"> has developed a mobile application that uses novel signal processing, computer vision technology, and a cloud-based AI engine to accurately assess a patient’s health parameters through a smartphone camera. This approach also attracted a significant investment of €1 million last year.</span></p><p><span lang="EN-GB">Ghent is home to other cutting-edge ventures embodying the fusion of scientific expertise and digital capabilities, which are revolutionising healthcare. Think about </span><a href="https://robovision.ai/"><span lang="EN-GB">Robovision</span></a><span lang="EN-GB">, collaborating closely with medical experts to translate ideas into state-of-the-art AI solutions, enabling precise organ detection and advanced decision support. Meanwhile, </span><a href="https://myneo.me/en"><span lang="EN-GB">myNEO</span></a><span lang="EN-GB">, a data-driven biotech startup, develops immunotherapies that train the immune system to combat tumour cells, identifying tumour epitope targets using biological datasets, neural networks, and specialised teams. Additionally, </span><a href="https://lizard.bio/services/"><span lang="EN-GB">BioLizard</span></a><span lang="EN-GB"> combines biological knowledge with expertise in bioinformatics, data analytics, AI, and software development to provide comprehensive drug and biomarker development solutions. They have expanded to the US by Supporting biotech and pharma companies.</span></p> </div> <div class="paragraph paragraph--type--image paragraph--view-mode--full"> <div class="image-gallery--wrapper single"> <div class="image-gallery js-lightbox"> <a href="https://stad.gent/sites/default/files/styles/gallery_full/public/media/images/Frame%204368.png?itok=mjQD6GpW" class="gallery-link" aria-describedby="image-gallery__open-gallery" > <figure> <picture> <source srcset="/sites/default/files/styles/wide_l/public/media/images/Frame%204368.png?itok=wm5HEmAA 1x, /sites/default/files/styles/wide_l_x2/public/media/images/Frame%204368.png?itok=ndjOLjCe 2x" media="(min-width: 1680px)" type="image/png" width="303" height="189"/> <source srcset="/sites/default/files/styles/wide_l/public/media/images/Frame%204368.png?itok=wm5HEmAA 1x, /sites/default/files/styles/wide_l_x2/public/media/images/Frame%204368.png?itok=ndjOLjCe 2x" media="all and (min-width: 960px) and (max-width: 1679.9px)" type="image/png" width="303" height="189"/> <source srcset="/sites/default/files/styles/wide_xxl/public/media/images/Frame%204368.png?itok=K4NxyJwU 1x, /sites/default/files/styles/wide_xxl_x2/public/media/images/Frame%204368.png?itok=bCReEjSq 2x" media="all and (min-width: 768px) and (max-width: 959.9px)" type="image/png" width="303" height="189"/> <source srcset="/sites/default/files/styles/wide_xl/public/media/images/Frame%204368.png?itok=p-J8CIMG 1x, /sites/default/files/styles/wide_xl_x2/public/media/images/Frame%204368.png?itok=K81_kVsc 2x" media="all and (min-width: 576px) and (max-width: 767.9px)" type="image/png" width="303" height="189"/> <source srcset="/sites/default/files/styles/wide_m/public/media/images/Frame%204368.png?itok=zE8WHkrv 1x, /sites/default/files/styles/wide_m_x2/public/media/images/Frame%204368.png?itok=HG5gog80 2x" media="all and (max-width: 575.9px)" type="image/png" width="303" height="189"/> <img loading="lazy" src="/sites/default/files/styles/wide_xxl_x2/public/media/images/Frame%204368.png?itok=bCReEjSq" width="303" height="189" alt="Invest in Ghent - A wealth of technologies - HealthTech" /> </picture> </figure> </a> </div> </div> </div> <div class="paragraph paragraph--type--text paragraph--view-mode--full"> <p><span lang="EN-GB">Ghent, with its abundant talent pool and accessible R&D funding, presents alluring investment prospects in the healthtech industry. The remarkable convergence of biotech, medtech, pharmaceuticals, healthcare, and the digital sector distinguishes the Ghent health region. As a flourishing epicentre, Ghent paves the path towards a healthier and brighter future, empowering its transformation into the European Technology Capital.</span></p> </div> <div class="paragraph paragraph--type--call-to-action paragraph--view-mode--full cta-block image-none link"> <div class="cta-block__content"> <div class="feature-block secondary"> <h2>Discover Invest in Ghent</h2> <p>Want to find out whether your business is a perfect match with our DNA? </p> <ul class="links"> <li> <a href="mailto:invest@stad.gent" class="button button-secondary">Contact Invest in Ghent!</a> </li> <li> <a href="https://youtu.be/5hXeqmFqplo" class="standalone-link">Find out more about healthtech in Ghent</a> </li> </ul> </div> </div> </div> " news.
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